Metallothionein-1g
Web5 mei 2014 · Metallothioneins (MT) are a family of low molecular weight proteins that share significant sequence homology, and are involved in zinc and redox metabolism ( 3) as well as in many aspects of cancer biology ( 4, 5 ). The human genome contains at least 11 functional MT genes that may be divided into four subgroups (MT1-4). WebMetallothionein-1G suppresses pancreatic cancer cell stemness by limiting activin A secretion via NF-κB inhibition. Article. Full-text available. Jan 2024; Kai Li; Zhicheng Zhang;
Metallothionein-1g
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Web16 mei 2016 · We observed that genes of the metallothionein-1 (MT1) family are induced in the HCC cell line Huh7 exposed to sorafenib. ... Bianchini M. Metallothionein 1G and zinc sensitize human colorectal cancer cells to chemotherapy. Mol Cancer Ther. 2014;13:1369–81. WebMetallothionein-1K,Metallothionein-IG,MT1G,MT1K, MT1M. Metallothioneins have a high content of cysteine residues that bind various heavy metals, ... Recombinant human …
WebAnti-MT1G antibodies are offered by a number of suppliers. This target gene encodes the protein 'metallothionein 1G' in humans and may also be known as MT1, MT1K, MT-1G, … WebHere, we show that metallothionein (MT)-1G is a critical regulator and promising therapeutic target of sorafenib resistance in human HCC cells. The expression of MT-1G …
WebMetallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. • … Web29 jul. 2014 · A PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation. We recently revealed that myeloid master regulator …
Web1 jan. 2024 · This study aimed to investigate metallothionein (MT)-1G involvement in the regulation of cancer stemness and provide a strategy to overcome chemoresistance in …
Web23 aug. 2024 · Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress. In humans, MTs have four main isoforms (MT1, MT2, MT3, and MT4) that are encoded by genes located on chromosome 16q13. furniture staging appWebDescription Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including positive regulation of cell migration involved in sprouting … furniture springfield moWeb8 okt. 2013 · Metallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway. October 2013; BMC Cancer 13(1):462; DOI: … furnitures stores near meWebNX_P13640 - MT1G - Metallothionein-1G - Medical. Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally … furniture staining charlotte nbcWebMetallothionein-1G suppresses pancreatic cancer cell stemness by limiting activin A secretion via NF-κB inhibition . Kai Li 1, Zhicheng Zhang 2, Yu Mei 1, Qingzhu Yang 1, Shupei Qiao 1, Cheng Ni 1, Yao Yao 1, Xinyuan Li 1, Mengmeng Li 1, Dongdong Wei 1, Wangjun Fu 1, Xuefei Guo 1, Xuemei Huang 1, Huanjie Yang 1, 1. furniture staging backdropWebNational Center for Biotechnology Information furniture srewsWeb5 okt. 2024 · For example, Sun et al. found that sorafenib treatment could induce the expression of Metallothionein-1G (MT-1G) in an Nrf2-dependent manner, which further contributed to the sorafenib resistance . furniture s.r.l. in italy