Webin phenytoin pharmacokinetics and/or efficacy and toxicity. Furthermore, phenytoin demonstrates non-linear pharmacokinetics even within the therapeutic range. The enzyme system involved in phenytoin metabolism gradually becomes saturated, resulting in a decrease in the rate of elimination of phenytoin as the dose is increased4. This means WebAug 1, 1995 · Differential AED effects on cognition were present for approximately one-third of the variables. Phenobarbital produced the worst performance; there was no clinically significant difference between phenytoin and valproate. NEUROLOGY 1995;45: 1494-1499 Copyright 1995 by Advanstar Communications Inc. View Full Text AAN Members
Amyloid-β: a potential link between epilepsy and cognitive ... - Nature
WebFeb 12, 2024 · Abstract. Cognitive impairment is one of the major problems associated with antiepileptic drugs. Phenytoin is one of the widely used anticonvulsant drugs, but it adversely affects learning and ... WebSep 2, 2024 · Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain. Phenytoin may also be used to treat certain types of irregular heartbeats. Phenytoin is available under the following different brand names: Dilantin, Dilantin 125, … track and trace covid scotland contact
Phenytoin Monograph for Professionals - Drugs.com
WebCognitive measures were also missing for 4 participants because of restrictions during the COVID-19 pandemic. Because of small samples and the lack of correction for multiple comparisons in the exploratory analysis, false-positive results and subgroup confounders are possible, and further evaluation of hypotheses generated from this study is ... WebA comparative study of the cognitive effects of phenytoin and carbamazepine in new referrals with epilepsy. Epilepsia. 1986;27(2):128–134. 76. Gillham RA, Williams N, Wiedmann KD, Butler E, Larkin JG, Brodie MJ. Cognitive function in adult epileptic patients established on anticonvulsant monotherapy. Epilepsy Res. 1990;7(3):219–225. 77. WebOct 18, 2024 · Phenytoin (Monograph) Brand names: Dilantin, Dilantin Infatabs, Phenytek Drug class: Hydantoins VA class: CN400 CAS number: 57-41-0 Medically reviewed by Drugs.com on Oct 18, 2024. Written by ASHP. Introduction Uses Dosage Warnings Interactions Stability Warning Cardiovascular Risk Associated with Rapid IV Administration track and trace deutsche post